A collaboration between the National Science Foundation (NSF) and the National Institutes of Health will give NIH-funded researchers training to help them evaluate their scientific discoveries for commercial potential, with the aim of accelerating biomedical innovations into applied health technologies.
 
I-Corps at NIH is a pilot of the NSF Innovation Corps (I-Corps) program specially tailored for biomedical research. Academic researchers and entrepreneurs with Small Business Innovation Research and Small Business Technology Transfer (SBIR/STTR) Phase I awards — awards that establish feasibility of proof of concept for commercializable technology — from participating NIH institutes will be eligible to apply to I-Corps at NIH. NIH will begin outreach to the small business research community with a June 25 program briefing at the 2014 BIO International Convention in San Diego, and a webinar on July 2.
 
The I-Corps Teams curriculum is a nine-week boot camp in which experienced business-savvy instructors work closely with teams of researchers to help them explore potential markets for their federally funded innovations. I-Corps instructors take a scientific method-based approach to customer discovery that resonates with scientists and engineers. While I-Corps instructors typically have a wide range of expertise, I-Corps at NIH will be taught by instructors who have biomedical business experience.
 
Providing tools for prospective entrepreneurs
The NIH institutes that will participate in the pilot program are the National Cancer Institute, the National Heart, Lung and Blood Institute, the National Institute of Neurological Disorders and Stroke, and the National Center for Advancing Translational Sciences.
 
Michael Weingarten, director of the NCI SBIR Development Center, said he and his colleagues initially reached out to NSF because they witnessed the difference I-Corps made for the graduates. To date, more than 300 three-person teams have completed the NSF I-Corps training, including those supported by the Department of Energy’s Advanced Research Projects Agency.
 
“I-Corps will help teach NIH-funded start-ups how to build scalable business models around new technologies they’re developing for the detection and treatment of disease. The program sheds new light on how companies can deal with important business risks such as protecting intellectual property, and developing regulatory and reimbursement strategies,” Mr. Weingarten said.
 
I-Corps will supplement SBIR/STTR awardees’ scientific skills through real time interactions with over 100 potential customers to validate their technology’s market potential. The 24 selected teams will receive supplemental funding from NIH to support entrepreneurial training, mentorship and collaboration opportunities.
 
“This new collaboration with NIH is further evidence of the flexibility and efficacy of the I-Corps model,” said Pramod Khargonekar, NSF assistant director for engineering.“Translating basic biomedical research to the marketplace has its own particular set of challenges, which we recognize. By focusing and adapting the I-Corps curriculum to the life sciences, we expect biomedical researchers will be better-equipped to enter the business arena.”
 
NIH awards more than $700 million in SBIR/STTR research and development awards each year. “This pilot will leverage NIH’s robust SBIR/STTR program and further NIH’s mission to advance our understanding of human illness and treatment of disease and disability,” said NIH SBIR/STTR program coordinator Matthew Portnoy. “We look forward to this collaborative endeavor with NSF.”
 
A sustainable innovation ecosystem
The I-Corps network continues to undergo strategic expansion. In addition to the pilot, existing NIH-funded programs can apply to become new NSF I-Corps sites to broaden the I-Corps network. These programs include the NIH Centers for Accelerated Innovation and Research Evaluation and Commercialization Hubs, which focus on academic researchers with technologies that have not yet led to the formation of a startup or have been licensed by an existing company.
 
All people and organizations involved in I-Corps become part of the NSF-established National Innovation Network, a nationwide web created to leverage the community that has developed among the grantees to increase the program’s impact.
 
NCI will lead outreach to the small business community in coming weeks, beginning with a briefing on the program at the 2014 BIO International Convention, the world’s largest gathering of the biotechnology industry, on June 25 from 2-3 p.m. PDT in San Diego and a webinar on July 2. Steve Blank, a serial entrepreneur and academic who developed the original course that I-Corps is based on, will participate in both events.