Palatinose, a slow, sustained-release carbohydrate called isomaltulose marketed by Beneo, was evidenced to improve certain aspects of sleep when consumed as a bedtime drink, compared to a high glycemic index beverage, according to a new clinical study.

The findings suggest that a more balanced blood glucose level, particularly during the first half of the night, Palatinose may support longer deep sleep phases, and therefore a more restful sleep.

Insomnia is prevalent in an estimated 10-30% of the population, though the number may be even as high as 50-60%, Beneo reported. Poor sleep quality is associated with obesity, impaired glucose metabolism, and dementia. With this in mind, the present study’s findings demonstrate that carbohydrate choices can possibly have an impact on sleep and mental well-being.

In the study, researchers compared the effects of either Palatinose isomaltulose or glucose on a person’s sleep. 20 healthy young men with a mean age of 24 years took part in the study, which was carried out in a double-blind, randomized, placebo-controlled, crossover fashion.

The participants’ blood glucose was measured continuously, and their sleep characteristic metrics were monitored in a laboratory setting using polysomnography and actigraphy.

One week after an acclimatization night in the lab setting, half of the men were given 50 grams of isomaltulose, or 50 grams of glucose, dissolved in a 300 ml drink of water. One week later, participants crossed over to the opposite drink. During each of the three nights, participants ate a standardized evening meal, and later viewed a series of neutral, positive, and negative stories. 15 minutes before bedtime, at approximately 11 p.m., the drinks were consumed, and in the morning, the story recall was tested.

Participants who consumed Palatinose had a slower and more sustained release of glucose in their blood, preventing dips in blood sugar levels, particularly during the first half of the night. Those who consumed Palatinose during the second intervention had extended deep sleep phases by an average of 22 minutes. Additionally, those who consumed Palatinose in the second intervention also had a better memory for neutral story content, the researchers found.

“These findings are significant, as deep or slow-wave sleep is important for physical recovery and cognitive health,” said Stephan Theis, PhD, head of nutrition science and communication at Beneo. “By supporting balanced blood sugar levels and prolonging the deep sleep phase, Palatinose may improve restful sleep and a person’s overall well-being. Its ability to sustain blood sugar levels overnight may also have far-reaching implications for dietary interventions, targeting sleep disorders and cognitive decline.”