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Specnova’s NooGandha significantly improved performance in subjects taking the COMPASS cognitive battery test after a single dose.
By: Mike Montemarano
September 20, 2024
A liposomal ashwagandha ingredient marketed as NooGandha by Specnova was associated with improved measures of cognition and mood, along with a strong safety profile, in a clinical study published in Nutrients. The study, conducted by Texas A&M University, University of Wisconsin, and Increnovo LLC, recruited 59 healthy men and women, with an average age of 22. In the randomized, double-blind trial, subjects either received 225 mg of NooGandha or a matching placebo. They were administered a fasting blood draw, and took part in the COMPASS cognitive function test battery, which included word recall, word recognition, choice reaction time task, picture recognition, digit vigilance task, Corsi Block test, and the Stroop test. They were also administered Profile of Mood States questionnaires. Tests were then repeated an hour after supplementation, and again after the subjects took NooGandha daily at the same dose for 30 days. “A single 225 mg dose of NooGandha improved picture and word recall, reaction time, and executive function,” said Sebastian Balcombe, MS, founder and CEO of Specnova. “Supplementing with NooGandha for 30 days further improved reaction time and executive function and significantly lowered tension and fatigue compared to placebo.” Balcombe attributed the results of this study, which found unique cognitive performance benefits compared to standard ashwagandha products, to the liposomal technology used to enhance the bioavailability of NooGandha at a low but more potent dosage. Additionally, “NooGandha’s superiority stems from a highly technical front-end vetting process that’s followed by the targeted extraction of key compounds from roots and leaves to produce only desired cognitive results, without the sleep-inducing and sedative effects often associated with ashwagandha.” “While our withanolide content is higher than any other products, according to the standardized USP/HPLC [USP High-Performance Liquid Chromatography] method, a variety of alkaloids and other bioactives also play an important role in making NooGandha higher-performing than other ashwagandhas,” Balcombe continued. “We know precisely what kinds of high-performance benefits manufacturers and consumers can expect from products containing NooGandha.” NooGandha is a suitable ingredient for products positioned for younger consumers drawn toward fast-acting, performance-boosting cognitive support solutions. “These consumers include college and graduate students, gamers, athletes, business professionals, and parents, all of whom are looking for quick decision making, better memory, an increase in focus, and improved reaction time,” Balcombe said. “Because NooGandha is fast-acting, as two of our published studies support, it’s the perfect ingredient for single-serving products in the cognitive performance, brain support, e-gaming, sports nutrition, and energy categories.”
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